Campesterol compound from Methanol Fraction of Brotowali (Tinospora crispa) Stem Bark
Authors: Weny J.A Musa, Suleman Duengo, Ahmad Kadir Kilo
Tinospora crispa is a plant of the Menispermaceae family which is one of the endemic plants in Indonesia, commonly called as Brotowali. Tinospora crispa have been used traditionally to treat fever, diabetes, rheumatism and sinusitis. The chemical components of the plant have not been reported so far. This study is intended to know the molecular structures of isolated compound of methanol fraction from T. crispa stem bark. Extraction using maceration method with n-hexana, ethyl acetate and methanol as a solvents. The chemical structures of compounds were elucidated with spectroscopic data (IR, 1H, 13C, DEPT 135ยบ, HMQC, HMBC, 1H-1H COSY NMR) and MS as well as compared with previously reported spectra data. and spectral data with the literature. In previously study, campesterol have anticholesterol and antiangiogenic activities.